In sufferers currently receiving an opioid analgesic, prescribe a lower initial dose of diazepam tablets than indicated from the absence of an opioid and titrate based upon medical response. If an opioid is initiated in a very individual previously taking diazepam tablets, prescribe a reduced Preliminary dose on the opioid and titrate dependent on

Elderly and really sick clients can possibly knowledge apnea or cardiac arrest. Concomitant usage of other central anxious program depressants improves this hazard. The smallest feasible efficient dose must be employed for this team of men and women.[fifty nine][60] The elderly metabolise benzodiazepines much more gradually than younger adults, and